… tool to study sialyltransferase function and related mechanisms. This review highlights
recent development of inhibitors of sialyltransferases reported since 2004. The inhibitors are …

… This demonstrates that small-molecule inhibitors of … inhibitors by design, from Nature and
from high-throughput screening (HTS), along with examining the emerging role of ST inhibitors …

… The elevated plasma sialyltransferase activities can be used as tumor … Some inhibitors of
sialyltransferases were found to be of … inhibitors, the sialyltransferase inhibitors can be also …

… β1-3)GlcNAcα(2,3)-sialyltransferase that controls CD8 þ T lym… mimetics as sialyltransferase
inhibitors is therefore desirable, … different types of sialyltransferase inhibitors that simulate the …

… of inhibitors against these enzymes, both based on the sialic acid scaffold and other small
molecule inhibitors… and discovery of such inhibitors, with a focus on inhibitors with a sialic acid-…

… Therefore, inhibiting STs has emerged as a potential strategy … in designing novel
sialyltransferase inhibitors using ligand-… ST inhibitors that hindered further development of ST …

… - versus O-selective sialyltransferase inhibitors. Inhibitor design entailed the functionalization
… Our results provide clear evidence that FCW34-induced sialyltransferase inhibition reduces …

… operate by specifically inhibiting sialyltransferase-mediated … in vivo effects of sialyltransferase
inhibition or knockdown on … and development of sialyltransferase inhibitors, their potential …

… sialyltransferase inhibitors. … inhibitors for (2-6)-sialyltransferase from rat liver. The K values
found are in the range of CDP which is thus far the most potent sialyltransferase inhibitor. …

… and their transformation into compounds of types A and B (ie, 1a,b and 2a,b, Scheme 3) are
outlined in this article; the inhibition properties of α(2−6)-sialyltransferase are also reported. …