[HTML][HTML] Signal pathways of melanoma and targeted therapy
W Guo, H Wang, C Li - Signal transduction and targeted therapy, 2021 - nature.com
Melanoma is the most lethal skin cancer that originates from the malignant transformation of
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with
few therapeutic options, increased biological understanding and unprecedented innovations
in therapies targeting mutated driver genes and immune checkpoints have substantially
improved the prognosis of patients. However, the low response rate and inevitable
occurrence of resistance to currently available targeted therapies have posed the obstacle in …
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with
few therapeutic options, increased biological understanding and unprecedented innovations
in therapies targeting mutated driver genes and immune checkpoints have substantially
improved the prognosis of patients. However, the low response rate and inevitable
occurrence of resistance to currently available targeted therapies have posed the obstacle in …
Signal pathways of melanoma and targeted therapy
G Weinan, H Wang, C Li - Signal Transduction and Targeted …, 2021 - search.proquest.com
Melanoma is the most lethal skin cancer that originates from the malignant transformation of
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with
few therapeutic options, increased biological understanding and unprecedented innovations
in therapies targeting mutated driver genes and immune checkpoints have substantially
improved the prognosis of patients. However, the low response rate and inevitable
occurrence of resistance to currently available targeted therapies have posed the obstacle in …
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with
few therapeutic options, increased biological understanding and unprecedented innovations
in therapies targeting mutated driver genes and immune checkpoints have substantially
improved the prognosis of patients. However, the low response rate and inevitable
occurrence of resistance to currently available targeted therapies have posed the obstacle in …
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