Cells of multicellular organisms have evolved highly organized plasma membranes with the
capacity to participate in diverse functions, such as formation of cell-cell junctions, localized
flux of ions, and polarized secretion of intracellular vesicles. Functions of the plasma
membrane requiring mechanical stability and long-range order cannot be explained by a
simple model of integral membrane proteins embedded in a fluid phospholipid bilayer. A
general conclusion from the last two decades of membrane research is that many integral …

Pages 1029–1065: Vann Bennett.“Spectrin-Based Membrane Skeleton: A Multipotential
Adaptor Between Plasma Membrane and Cytoplasm.” Page 1056: Ref. 36 should read
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