Spontaneous preterm birth: advances toward the discovery of genetic predisposition

JF Strauss III, R Romero, N Gomez-Lopez… - American journal of …, 2018 - Elsevier
Evidence from family and twin-based studies provide strong support for a significant
contribution of maternal and fetal genetics to the timing of parturition and spontaneous
preterm birth. However, there has been only modest success in the discovery of genes
predisposing to preterm birth, despite increasing sophistication of genetic and genomic
technology. In contrast, DNA variants associated with other traits/diseases have been
identified. For example, there is overwhelming evidence that suggests that the nature and …
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