… Tablets can be manufactured by direct compression or via dry, wet or melt granulation of
drug(s)/excipient(s) mixture. Direct compression is a simple, quick and cost-effective method of …

… The objective of this study was to prepare and evaluate a novel spray-dried direct compression
… available spray-dried lactose is one of the very commonly used direct compression …

… by co-spray drying and evaluated on spray drying processibility, … parameters during spray
drying on the compaction behaviour of drug/… of co-spray dried powders for direct compression. …

… Within pharmaceutical and biopharmaceutical industry spray drying is often selected to
transform the active pharmaceutical … Several co-spray dried excipients for direct compression are …

… metformin hydrochloride capable of being directly compressed into strong tablets with an …
produce drug crystals with improved compaction properties and suitable for direct compression…

… Spray-dried lactose is produced by spray drying the … the spray-dried lactose is responsible
for the better binding and plastic deformation. Compressibility is affected if it is allowed to dry …

… are agglomerated into spheres by spray drying. Because it is much … spray-direct lactose in
many new direct-compression formulations. Because of the spherical nature of the spray-dried …

… The presence of moisture in pharmaceutical powders can also play a significant role on the
… in order to obtain a material for direct compression, and then to explain the reasons for its …

… It is produced by spray drying of a 95% anhydrous β-lactose and 5% anhydrous lactitol
solution. It is available in different grades depending on the particle size Citation20 . For example…

… with that of spray-dried lactose as an excipient in the direct compression of tablets. … spray-dried
lactose in some formulations. Dextrose was found to give less browning than spraydried …