Background Statin therapy for sepsis has been suggested by observational studies.
However, randomized controlled trials have not demonstrated this benefit. We conducted a
systematic review and meta-analysis of randomized trials to evaluate the effect of statin
therapy on mortality in patients with sepsis. Methods We searched 6 electronic databases for
articles published before August 2014. Randomized trials reporting the effect of statin
therapy on mortality in patients with sepsis were included. The primary outcome of interest …