Study characteristics influence the efficacy of substance abuse treatments: a meta-analysis of medications for alcohol use disorder
EM Klemperer, JR Hughes, S Naud - Drug and alcohol dependence, 2018 - Elsevier
Background Understanding study characteristics' influence on treatment efficacy could
improve methodologies and interpretation of findings. We examine study characteristics as
predictors of outcomes in clinical trials of medications for alcohol problems. Methods We
obtained data on 23 trials of naltrexone and 22 trials of acamprosate from Cochrane
reviews. We extracted data for 14 study characteristics and 3 dependent variables (odds
ratio; percent abstinent in placebo; medication conditions). We used general linear models …
improve methodologies and interpretation of findings. We examine study characteristics as
predictors of outcomes in clinical trials of medications for alcohol problems. Methods We
obtained data on 23 trials of naltrexone and 22 trials of acamprosate from Cochrane
reviews. We extracted data for 14 study characteristics and 3 dependent variables (odds
ratio; percent abstinent in placebo; medication conditions). We used general linear models …
Study characteristics influence the efficacy of substance abuse treatments: a meta-analysis of medications for smoking cessation
EM Klemperer, JR Hughes… - Nicotine and Tobacco …, 2020 - academic.oup.com
Background Understanding study characteristics' influence on treatment efficacy could
improve interpretation of trials' outcomes. We examined study characteristics as predictors of
outcomes in clinical trials of medications for tobacco use. Methods We obtained and
analyzed data on 44 trials of nicotine gum, 37 trials of nicotine patch, 27 trials of varenicline,
and 43 trials of bupropion from Cochrane reviews. We extracted and analyzed data for 15
study characteristics, odds ratios (ORs), and percent abstinent in control and medication …
improve interpretation of trials' outcomes. We examined study characteristics as predictors of
outcomes in clinical trials of medications for tobacco use. Methods We obtained and
analyzed data on 44 trials of nicotine gum, 37 trials of nicotine patch, 27 trials of varenicline,
and 43 trials of bupropion from Cochrane reviews. We extracted and analyzed data for 15
study characteristics, odds ratios (ORs), and percent abstinent in control and medication …
以上显示的是最相近的搜索结果。 查看全部搜索结果