To assess subendocardial (long-axis) and mid-wall (short-axis) left ventricular (LV) function
in patients with type 1 myotonic dystrophy (MD1), with no symptoms or clinical signs of heart
disease, to investigate if they have subclinical cardiac involvement, 28 subjects (14 with
MD1, and 14 age-and sex-matched normals) had conventional and tissue Doppler
echocardiography. Myocardial velocities and timings to peak systolic contractions were
measured. LV wall thickness, diameters, and ejection fraction were not different between the …