Succinic Ester‐Based Shape Memory Gelatin Sponge for Noncompressible Hemorrhage without Hindering Tissue Regeneration
Y Zhu, L Zhang, W Duan… - Advanced …, 2023 - Wiley Online Library
Shape memory sponges are very promising in stopping the bleeding from noncompressible
and narrow entrance wounds. However, few shape memory sponges have fast degradable
properties in order to not hinder tissue healing. In this work, based on cryopolymerization, a
succinic ester‐based sponge (Ssponge) is fabricated using gelatin and bi‐polyethylene
glycol‐succinimidyl succinate (Bi‐PEG‐SS). Compared with the commercially available
gelatin sponge (Csponge), Ssponge possesses better water/blood absorption ability and …
and narrow entrance wounds. However, few shape memory sponges have fast degradable
properties in order to not hinder tissue healing. In this work, based on cryopolymerization, a
succinic ester‐based sponge (Ssponge) is fabricated using gelatin and bi‐polyethylene
glycol‐succinimidyl succinate (Bi‐PEG‐SS). Compared with the commercially available
gelatin sponge (Csponge), Ssponge possesses better water/blood absorption ability and …
Succinic Ester‐Based Shape Memory Gelatin Sponge for Noncompressible Hemorrhage without Hindering Tissue Regeneration (Adv. Healthcare Mater. 5/2023)
Y Zhu, L Zhang, W Duan… - Advanced …, 2023 - Wiley Online Library
In article 2202122, Xifu Zheng, Yazhong Bu, and co-workers successfully develop a fast
degradable shape memory sponge for noncompressible hemorrhage without hindering
tissue regeneration. The resulting sponge possesses high mechanical stability and
hemostatic efficiency. Meanwhile, its fast degradation, resulting from succinic esters, leads to
fast tissue regeneration when compared with a commercialized sponge. This sponge is
composed of components with well-identified biocompatibility, making it very promising in …
degradable shape memory sponge for noncompressible hemorrhage without hindering
tissue regeneration. The resulting sponge possesses high mechanical stability and
hemostatic efficiency. Meanwhile, its fast degradation, resulting from succinic esters, leads to
fast tissue regeneration when compared with a commercialized sponge. This sponge is
composed of components with well-identified biocompatibility, making it very promising in …
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