Superparamagnetic nanoparticle assisted hyperthermia and cooling protocol for optimum damage of internal carcinoma using computational predictive model
Heat and Mass Transfer, 2013•Springer
A predictive model has been developed for superparamagnetic nanoparticle assisted
hyperthermia in presence of external electromagnetic field to affect necrosis of internal
carcinoma. Effect of different parameters on tissue temperature rise is tested and finally
damage is analyzed to get a definitive measure of tissue destruction. A cooling protocol has
been predicted to obtain maximum tumor destruction while maintaining minimum damage of
the healthy tissue. We propose the comprehensive modeling strategy outlined here as the …
hyperthermia in presence of external electromagnetic field to affect necrosis of internal
carcinoma. Effect of different parameters on tissue temperature rise is tested and finally
damage is analyzed to get a definitive measure of tissue destruction. A cooling protocol has
been predicted to obtain maximum tumor destruction while maintaining minimum damage of
the healthy tissue. We propose the comprehensive modeling strategy outlined here as the …
Abstract
A predictive model has been developed for superparamagnetic nanoparticle assisted hyperthermia in presence of external electromagnetic field to affect necrosis of internal carcinoma. Effect of different parameters on tissue temperature rise is tested and finally damage is analyzed to get a definitive measure of tissue destruction. A cooling protocol has been predicted to obtain maximum tumor destruction while maintaining minimum damage of the healthy tissue. We propose the comprehensive modeling strategy outlined here as the precursor to the development of efficient therapeutic planning tools for cancer patients.
Springer
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