Surface antigens of a filarial nematode: analysis of adult Brugia pahangi surface components and their use in monoclonal antibody production
I Sutanto, RM Maizels, DA Denham - Molecular and Biochemical …, 1985 - Elsevier
The surface antigens of adult worms of the filarial nematode Brugia pahangi have been
investigated further by surface radioiodination and detergent solubilisation techniques. In
addition to yielding new information on the distribution of antigenic components of this stage,
detergent-solubilised molecules were used in both radiometric and enzyme-linked assays
for human and mouse antibody. These assays were subsequently used in screening for
monoclonal antibodies from hybrid cells derived from animals infected with living parasites …
investigated further by surface radioiodination and detergent solubilisation techniques. In
addition to yielding new information on the distribution of antigenic components of this stage,
detergent-solubilised molecules were used in both radiometric and enzyme-linked assays
for human and mouse antibody. These assays were subsequently used in screening for
monoclonal antibodies from hybrid cells derived from animals infected with living parasites …
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