INTRODUCTION: Despite significant advances, widespread applicability of islet cell
transplantation remains elusive. Refinement of current islet isolation protocols may improve
transplant outcomes. Islet purification by magnetic separation has shown early promise.
However, surgical protocols must be optimized to maximize the incorporation of
paramagnetic microparticles (MP) within a greater number of islets. This study explores the
impact of MP concentration and infusion method on optimizing MP incorporation within …