Synthesis of chitosan-alginate microspheres with high antimicrobial and antibiofilm activity against multi-drug resistant microbial pathogens

R Thaya, B Vaseeharan, J Sivakamavalli… - Microbial …, 2018 - Elsevier
The successful treatment of multi-drug resistant microbial pathogens represents a major
challenge for public health management. Here, chitosan-alginate (CS/ALG) microspheres
with narrow size distribution were fabricated by ionically cross linking method using Ca 2+
ions as agents for polymer solidification. The physicochemical properties of CS/ALG
microspheres, such as surface morphology and size, were studied by SEM. The functional
group interactions were confirmed by Fourier transform infrared (FTIR) spectroscopy. SEM …
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