System-wide changes to SUMO modifications in response to heat shock
Covalent conjugation of the small ubiquitin-like modifier (SUMO) proteins to target proteins
regulates many important eukaryotic cellular mechanisms. Although the molecular
consequences of the conjugation of SUMO proteins are relatively well understood, little is
known about the cellular signals that regulate the modification of their substrates. Here, we
show that SUMO-2 and SUMO-3 are required for cells to survive heat shock. Through
quantitative labeling techniques, stringent purification of SUMOylated proteins, advanced …
regulates many important eukaryotic cellular mechanisms. Although the molecular
consequences of the conjugation of SUMO proteins are relatively well understood, little is
known about the cellular signals that regulate the modification of their substrates. Here, we
show that SUMO-2 and SUMO-3 are required for cells to survive heat shock. Through
quantitative labeling techniques, stringent purification of SUMOylated proteins, advanced …
[PDF][PDF] System-wide changes to SUMO modifications in response to heat shock
Covalent conjugation of the small ubiquitin-like modifier (SUMO) proteins to target proteins
regulates many important eukaryotic cellular mechanisms. Although the molecular
consequences of the conjugation of SUMO proteins are relatively well understood, little is
known about the cellular signals that regulate the modification of their substrates. Here, we
show that SUMO-2 and SUMO-3 are required for cells to survive heat shock. Through
quantitative labeling techniques, stringent purification of SUMOylated proteins, advanced …
regulates many important eukaryotic cellular mechanisms. Although the molecular
consequences of the conjugation of SUMO proteins are relatively well understood, little is
known about the cellular signals that regulate the modification of their substrates. Here, we
show that SUMO-2 and SUMO-3 are required for cells to survive heat shock. Through
quantitative labeling techniques, stringent purification of SUMOylated proteins, advanced …
以上显示的是最相近的搜索结果。 查看全部搜索结果