Systematical engineering of synthetic yeast for enhanced production of lycopene

Y Zhang, TY Chiu, JT Zhang, SJ Wang, SW Wang… - Bioengineering, 2021 - mdpi.com
… into yeastimproved yeast phenotype. Here, in our study, we explored the potential of utilizing
this unique system built in the synthetic yeast strain to quickly improve lycopene production

[PDF][PDF] Systematical Engineering of Synthetic Yeast for Enhanced Production of Lycopene. Bioengineering 2021, 8, 14

Y Zhang, TY Chiu, JT Zhang, SJ Wang, SW Wang… - 2021 - researchgate.net
… into yeastimproved yeast phenotype. Here, in our study, we explored the potential of utilizing
this unique system built in the synthetic yeast strain to quickly improve lycopene production

Multi-modular metabolic engineering and efflux engineering for enhanced lycopene production in recombinant Saccharomyces cerevisiae

G Huang, J Li, J Lin, C Duan… - Journal of Industrial …, 2024 - academic.oup.com
… , lycopene production in yeast was markedly enhanced by … In this study, aimed at enhancing
the lycopene yield of S. cere… Systematical engineering of synthetic yeast for enhanced

Iterative gene integration mediated by 26S rDNA and non-homologous end joining for the efficient production of lycopene in Yarrowia lipolytica

Z Luo, JT Shi, XL Chen, J Chen, F Liu, LJ Wei… - Bioresources and …, 2023 - Springer
… study, we improved lycopene production in Y. lipolytica using efficient gene editing tools
and effective engineering … In this study, we systematically engineered Y. lipolytica for high-yield …

From Yeast to Biotechnology

A Patel, U Rova, P Christakopoulos, L Matsakas - Bioengineering, 2022 - mdpi.com
… (2021) applied Synthetic Chromosome Rearrangement … lycopene biosynthesis in the model
yeast S. cerevisiae strain YSy 200, which resulted in a final yield of 41.47 mg/L of lycopene. …

Alleviation of metabolic bottleneck by combinatorial engineering enhanced astaxanthin synthesis in Saccharomyces cerevisiae

P Zhou, W Xie, A Li, F Wang, Z Yao, Q Bian… - Enzyme and Microbial …, 2017 - Elsevier
… By creating and integrating the positive CrtE mutant CrtE03M into the lycopene biosynthesis
pathway, a 2.2-fold enhancement of lycopene accumulation was achieved in S. cerevisiae […

Engineering Biology of Yeast for Advanced Biomanufacturing

W Jiang, Y Li, H Peng - Bioengineering, 2022 - mdpi.com
lycopene biosynthesis pathway. The expression of the optimized lycopene biosynthesis
pathway improved the lycopene … In addition, a semi-synthetic yeast strain harboring a synthetic

Biotechnological approaches for producing natural pigments in yeasts

A Bernard, T Rossignol, YK Park - Trends in Biotechnology, 2024 - cell.com
… cerevisiae, a similar strategy was used to improved lycopene accumulation by engineering
triacylglycerol metabolism [38]. Alternatively, adding oleic acid to the cultivation in order to …

Golden Gate Cloning for Efficient Biosynthesis of Lycopene in Synthetic Yeast

Y Zhang, J Zheng, X Fu, Y Shen - Golden Gate Cloning: Methods and …, 2024 - Springer
… and improving lycopene production in the synthetic yeast chassis. … lycopene pathway
into a SCRaMbLEd-optimized synthetic yeast to achieve increased production of lycopene. …

Combinatorial optimization of gene expression through recombinase-mediated promoter and terminator shuffling in yeast

C Cautereels, J Smets, P Bircham… - Nature …, 2024 - nature.com
… Specifically, upregulation of CrtI expression was linked to increased levels of lycopene, … of
CrtZ expression correlated with increased astaxanthin levels (Pearson correlation test with p = …