TLR-3 stimulation skews M2 macrophages to M1 through IFN-αβ signaling and restricts tumor progression
A Vidyarthi, N Khan, T Agnihotri, S Negi… - Frontiers in …, 2018 - frontiersin.org
… of TLR-3 in the reversion of M2-macrophages to M1. We analyzed the role of TLR-3 stimulation
for skewing M2-macrophages to M1 at mRNA and protein level through qRT-PCR, flow …
for skewing M2-macrophages to M1 at mRNA and protein level through qRT-PCR, flow …
Major pathways involved in macrophage polarization in cancer
C Kerneur, CE Cano, D Olive - Frontiers in immunology, 2022 - frontiersin.org
… of M2 macrophages. Moreover, macrophage plasticity is supported by stimuli from the Tumor
… section the main signaling pathways involved in M1-macrophage polarization in humans …
… section the main signaling pathways involved in M1-macrophage polarization in humans …
Molecular repolarisation of tumour-associated macrophages
FJ Van Dalen, MHME Van Stevendaal, FL Fennemann… - Molecules, 2018 - mdpi.com
… , M1 polarised macrophages recruit new T h 1 cells via … On the other end of the spectrum
are M2 macrophages. This … of inducing M1 polarisation is through stimulation with TLR …
are M2 macrophages. This … of inducing M1 polarisation is through stimulation with TLR …
[HTML][HTML] Intratumoral immunotherapy using a TLR2/3 agonist, L-pampo, induces robust antitumor immune responses and enhances immune checkpoint blockade
WS Lee, DS Kim, JH Kim, Y Heo, H Yang… - … of cancer, 2022 - ncbi.nlm.nih.gov
… Immune responses to stimulation with various TLR agonists were compared. … efficacy by
activating tumor-specific CD8 + T cells and enhancing M1-like macrophages within the tumor …
activating tumor-specific CD8 + T cells and enhancing M1-like macrophages within the tumor …
TLR-3 stimulation skews M2 macrophages to M1 through IFN-αβ signaling and restricts tumor progression
D Chatterjee, OR Colegio, MK Tewari, T Agnihotri… - 2018 - dspace.iitrpr.ac.in
… of TLR-3 in the reversion of M2-macrophages to M1. We analyzed the role of TLR-3 stimulation
for skewing M2-macrophages to M1 at mRNA and protein level through qRT-PCR, flow …
for skewing M2-macrophages to M1 at mRNA and protein level through qRT-PCR, flow …
Investigating The Possible Effect of Gak-3βinhibitor on Macrophage Transformation Via TLR3 and 4 Signaling Pathway
Y Liu, M Zhou, B Wang, D Huo, M Ha - Proceedings of the 2021 8th …, 2021 - dl.acm.org
… macrophage from protumor forming m2 to antitumour M1 and IFN - αβ This paper leads to
the suppression of the tumor … therapeutic role of TLR-3 in the treatment of tumors. INF - αβ …
the suppression of the tumor … therapeutic role of TLR-3 in the treatment of tumors. INF - αβ …
[HTML][HTML] Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer
… of M2-like macrophages that were stimulated to transform into … do not transform into the M2
phenotype through the Notch signaling … Stimulation of TLR-3 polarizes macrophages to an M1 …
phenotype through the Notch signaling … Stimulation of TLR-3 polarizes macrophages to an M1 …
Directing toll-like receptor signaling in macrophages to enhance tumor immunotherapy
Q Zeng, CM Jewell - Current opinion in biotechnology, 2019 - Elsevier
… Generally speaking, M2-like macrophages support tumor … of unique macrophage phenotypes
can be generated by stimulation … to M1-like macrophages in mice, leading to reduced tumor …
can be generated by stimulation … to M1-like macrophages in mice, leading to reduced tumor …
[HTML][HTML] Targeting innate immune pathways for cancer immunotherapy
LL Cao, JC Kagan - Immunity, 2023 - cell.com
… wherein distinct innate immune signaling pathways activate five key … cold tumors into
inflammatory T cell-enriched “hot” tumors. … in DCs that are needed to stimulate new and long-lived …
inflammatory T cell-enriched “hot” tumors. … in DCs that are needed to stimulate new and long-lived …
Reprogramming the tumor microenvironment with biotechnology
… Tumor cells stimulate major molecular, cellular and physical … -tumor M2 into anti-tumor
M1-like macrophages (Fig. 2b) [39]. … a TLR-3 triggering reverts human M2 to M1. The size of the …
M1-like macrophages (Fig. 2b) [39]. … a TLR-3 triggering reverts human M2 to M1. The size of the …