[HTML][HTML] TNFα/TNFR1 signal induces excessive senescence of decidua stromal cells in recurrent pregnancy loss
S Zeng, Y Liang, S Lai, S Bi, L Huang, Y Li… - Journal of Reproductive …, 2023 - Elsevier
Defects in decidual response are associated with adverse pregnancy outcomes which
includes recurrent pregnancy loss (RPL). It is reported that cellular senescence happens
during decidualization and pro-senescent decidual response in the luteal phase
endometrium is related to RPL. However, the underlying mechanisms of how excessive
decidual senescence takes place in RPL decidua cells remain largely unexplored. The
senescent phenotype of RPL decidua and tumor necrosis factor receptor 1 (TNFR1) …
includes recurrent pregnancy loss (RPL). It is reported that cellular senescence happens
during decidualization and pro-senescent decidual response in the luteal phase
endometrium is related to RPL. However, the underlying mechanisms of how excessive
decidual senescence takes place in RPL decidua cells remain largely unexplored. The
senescent phenotype of RPL decidua and tumor necrosis factor receptor 1 (TNFR1) …
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