Taking cyclotron 68Ga production to the next level: Expeditious solid target production of 68Ga for preparation of radiotracers
BJB Nelson, J Wilson, S Richter, MJM Duke… - Nuclear Medicine and …, 2020 - Elsevier
Introduction Gallium-68 is an important radionuclide for positron emission tomography (PET)
with steadily increasing applications of 68 Ga-based radiopharmaceuticals for clinical use.
Current 68 Ga sources are primarily 68 Ge/68 Ga-generators, along with successful attempts
of 68 Ga production using a cyclotron. This study evaluated cyclotron 68 Ga production and
automated separation using expeditiously manufactured solid targets, demonstrates an
order of magnitude improvement in yield compared to 68 Ge/68 Ga generators, and …
with steadily increasing applications of 68 Ga-based radiopharmaceuticals for clinical use.
Current 68 Ga sources are primarily 68 Ge/68 Ga-generators, along with successful attempts
of 68 Ga production using a cyclotron. This study evaluated cyclotron 68 Ga production and
automated separation using expeditiously manufactured solid targets, demonstrates an
order of magnitude improvement in yield compared to 68 Ge/68 Ga generators, and …
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