In the search for anti-SARS-CoV, tanshinones derived from Salvia miltiorrhiza were found to
be specific and selective inhibitors for the SARS-CoV 3CLpro and PLpro, viral cysteine
proteases. A literature search for studies involving the seven isolated tanshinone hits
showed that at present, none have been identified as coronaviral protease inhibitors. We
have identified that all of the isolated tanshinones are good inhibitors of both cysteine
proteases. However, their activity was slightly affected by subtle changes in structure and …

Tanshinones as selective and slow binding inhibitors for SARS-CoV cysteine proteases -
학지사ㆍ교보문고 스콜라 … (2012년) Tanshinones as selective and slow binding inhibitors
for SARS-CoV cysteine proteases … Tanshinones as selective and slow binding inhibitors
for SARS-CoV cysteine proteases …