… Targeted locus amplification (TLA) is a … locus-specific sequence. In combination with
next-generation sequencing, TLA enables the complete sequencing and haplotyping of targeted …

… We have used targeted locus amplification (TLA) to efficiently map the transgene location
in seven previously published Cre and CreERT2 transgenic lines. In all lines, transgene …

Targeted locus amplification (TLA) allows for the detection of all genetic variation (including
structural variation) in a genomic region of interest. As TLA is based on proximity ligation, …

… We report an efficient NGS workflow applying the targeted locus amplification (TLA) strategy
… allows for targeted sequencing of genomic integrated transgenic DNA without prior locus …

… The recently developed targeted locus amplification (TLA) technology is … amplification and
sequencing of entire genes on the basis of the crosslinking of physically proximal DNA loci, …

… Here, we describe the use of Targeted Locus Amplification (TLA), combined with deep-sequencing
to detect fusion genes and sequence mutations relevant for stratification of BCP-ALL. …

… A recently reported technique, targeted locus amplification (TLA), enables … by targeted
amplification using outward-orientated primers and subsequent sequencing of any locus of interest…

… targeted locus amplification (TLA) technology [de Vree PJ, Nat Biotechnol 2014] that selectively
amplifies … of the crosslinking of physically proximal DNA loci, was able to identify novel …

… During this study, we have used a relatively new technique named targeted locus amplification
(TLA) to pinpoint deletion breakpoints in the α-globin-gene cluster, allowing accurate …

… patient-specific targets can be identified using targeted locus amplification in different pediatric
solid tumors. Furthermore, we show that these patient-specific targets can be detected in …