A molecular imaging primer: modalities, imaging agents, and applications
ML James, SS Gambhir - Physiological reviews, 2012 - journals.physiology.org
… or in combination with targeted imaging agents, to visualize … The data generated from
molecular imaging studies can be … Due to space constraints, this review will focus on molecular …
molecular imaging studies can be … Due to space constraints, this review will focus on molecular …
Nanoplatforms for targeted molecular imaging in living subjects
… agents will be included in this Review. … targeting can be achieved by attaching targeting
molecules to the QD surface. However, in vivo targeting and imaging is very challenging due to …
molecules to the QD surface. However, in vivo targeting and imaging is very challenging due to …
Principles in the design of ligand-targeted cancer therapeutics and imaging agents
M Srinivasarao, CV Galliford, PS Low - Nature reviews Drug discovery, 2015 - nature.com
… and development of low-molecular-weight ligand-targeted cancer therapeutics and, in …
Whereas a non-cleavable bridge between a ligand and an attached imaging agent is generally …
Whereas a non-cleavable bridge between a ligand and an attached imaging agent is generally …
High-throughput in vivo screening of targeted molecular imaging agents
MKJ Gagnon, SH Hausner, J Marik… - Proceedings of the …, 2009 - National Acad Sciences
… related … molecular imaging agent or agents from a large number of candidates is a reality.
This approach negates the dependence on lead compounds derived from known ligand/target …
This approach negates the dependence on lead compounds derived from known ligand/target …
Targeted molecular imaging agents for cellular-scale bimodal imaging
HC Manning, T Goebel, RC Thompson… - Bioconjugate …, 2004 - ACS Publications
… using a PBR ligand would be particularly attractive due to the … first PBR-targeted MI agent
that could facilitate MR imaging and, … -scale bimodal (MR and fluorescence) imaging. The MI …
that could facilitate MR imaging and, … -scale bimodal (MR and fluorescence) imaging. The MI …
Folate-mediated targeting of therapeutic and imaging agents to cancers
… When FA is covalently linked via its y-carboxyl to a drug or imaging agent, FR …
targeting ligand for the specific delivery to cancer cells of protein toxins, imaging agents, low-molecular…
targeting ligand for the specific delivery to cancer cells of protein toxins, imaging agents, low-molecular…
Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics
A Hellebust, R Richards-Kortum - Nanomedicine, 2012 - Taylor & Francis
… of the molecular changes associated with cancer … cancer therapeutics targeted against specific
molecular pathways; … been explored to target optical molecular imaging agents; sensitivity …
molecular pathways; … been explored to target optical molecular imaging agents; sensitivity …
Targeted contrast agents for magnetic resonance molecular imaging of cancer
… We have identified a promising lead targeted GBCA, ZD2-N3-Gd(HP-DO3A) … molecular
imaging agents. The prior effort of designing targeted MRI CAs was mainly focused on targeting …
imaging agents. The prior effort of designing targeted MRI CAs was mainly focused on targeting …
A review of imaging agent development
ED Agdeppa, ME Spilker - The AAPS journal, 2009 - Springer
… true for molecular imaging agents that bind to a specific target in vivo. For example, target …
profits from diagnostic imaging agents compared to those associated with pharmaceuticals. …
profits from diagnostic imaging agents compared to those associated with pharmaceuticals. …
Molecular magnetic resonance imaging with targeted contrast agents
D Artemov - Journal of cellular biochemistry, 2003 - Wiley Online Library
… These nanoparticles are targeted to the receptor by MAb attached via biotin-avidin linkers. …
vivo, however the large molecular size of this CA may prevent its use for imaging cell-surface …
vivo, however the large molecular size of this CA may prevent its use for imaging cell-surface …