A molecular imaging primer: modalities, imaging agents, and applications

ML James, SS Gambhir - Physiological reviews, 2012 - journals.physiology.org
… or in combination with targeted imaging agents, to visualize … The data generated from
molecular imaging studies can be … Due to space constraints, this review will focus on molecular

Nanoplatforms for targeted molecular imaging in living subjects

W Cai, X Chen - Small, 2007 - Wiley Online Library
agents will be included in this Review. … targeting can be achieved by attaching targeting
molecules to the QD surface. However, in vivo targeting and imaging is very challenging due to …

Principles in the design of ligand-targeted cancer therapeutics and imaging agents

M Srinivasarao, CV Galliford, PS Low - Nature reviews Drug discovery, 2015 - nature.com
… and development of low-molecular-weight ligand-targeted cancer therapeutics and, in …
Whereas a non-cleavable bridge between a ligand and an attached imaging agent is generally …

High-throughput in vivo screening of targeted molecular imaging agents

MKJ Gagnon, SH Hausner, J Marik… - Proceedings of the …, 2009 - National Acad Sciences
relatedmolecular imaging agent or agents from a large number of candidates is a reality.
This approach negates the dependence on lead compounds derived from known ligand/target

Targeted molecular imaging agents for cellular-scale bimodal imaging

HC Manning, T Goebel, RC Thompson… - Bioconjugate …, 2004 - ACS Publications
… using a PBR ligand would be particularly attractive due to the … first PBR-targeted MI agent
that could facilitate MR imaging and, … -scale bimodal (MR and fluorescence) imaging. The MI …

Folate-mediated targeting of therapeutic and imaging agents to cancers

JA Reddy, PS Low - Critical Reviews™ in Therapeutic Drug …, 1998 - dl.begellhouse.com
… When FA is covalently linked via its y-carboxyl to a drug or imaging agent, FR …
targeting ligand for the specific delivery to cancer cells of protein toxins, imaging agents, low-molecular

Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics

A Hellebust, R Richards-Kortum - Nanomedicine, 2012 - Taylor & Francis
… of the molecular changes associated with cancer … cancer therapeutics targeted against specific
molecular pathways; … been explored to target optical molecular imaging agents; sensitivity …

Targeted contrast agents for magnetic resonance molecular imaging of cancer

ZR Lu, V Laney, Y Li - Accounts of chemical research, 2022 - ACS Publications
… We have identified a promising lead targeted GBCA, ZD2-N3-Gd(HP-DO3A) … molecular
imaging agents. The prior effort of designing targeted MRI CAs was mainly focused on targeting

A review of imaging agent development

ED Agdeppa, ME Spilker - The AAPS journal, 2009 - Springer
… true for molecular imaging agents that bind to a specific target in vivo. For example, target
profits from diagnostic imaging agents compared to those associated with pharmaceuticals. …

Molecular magnetic resonance imaging with targeted contrast agents

D Artemov - Journal of cellular biochemistry, 2003 - Wiley Online Library
… These nanoparticles are targeted to the receptor by MAb attached via biotin-avidin linkers. …
vivo, however the large molecular size of this CA may prevent its use for imaging cell-surface …