Targeting the potassium ion channel genes SK and SH as a novel approach for control of insect pests: efficacy and biosafety
B Alshukri, F Astarita, M Al‐Esawy… - Pest management …, 2019 - Wiley Online Library
BACKGROUND Potassium ion channels play a critical role in the generation of electrical
signals and thus provide potential targets for control of insect pests by RNA interference.
RESULTS Genes encoding the small conductance calcium‐activated potassium channel
(SK) and the voltage‐gated potassium channel (SH) were knocked down in Tribolium
castaneum by injection and oral delivery of dsRNA (dsTcSK and dsTcSH, respectively).
Irrespective of the delivery mechanism a dose‐dependent effect was observed for …
signals and thus provide potential targets for control of insect pests by RNA interference.
RESULTS Genes encoding the small conductance calcium‐activated potassium channel
(SK) and the voltage‐gated potassium channel (SH) were knocked down in Tribolium
castaneum by injection and oral delivery of dsRNA (dsTcSK and dsTcSH, respectively).
Irrespective of the delivery mechanism a dose‐dependent effect was observed for …
[PDF][PDF] Targeting the potassium ion channel genes SK and SH as a novel approach for control of insect pests: efficacy and biosafety
MES Abd El Halim, F Pennacchio, AMR Gatehousea… - 2019 - academia.edu
BACKGROUND: Potassium ion channels play a critical role in the generation of electrical
signals and thus provide potential targets for control of insect pests by RNA interference.
RESULTS: Genes encoding the small conductance calcium-activated potassium channel
(SK) and the voltage-gated potassium channel (SH) were knocked down in Tribolium
castaneum by injection and oral delivery of dsRNA (dsTcSK and dsTcSH, respectively).
Irrespective of the delivery mechanism a dose-dependent effect was observed for …
signals and thus provide potential targets for control of insect pests by RNA interference.
RESULTS: Genes encoding the small conductance calcium-activated potassium channel
(SK) and the voltage-gated potassium channel (SH) were knocked down in Tribolium
castaneum by injection and oral delivery of dsRNA (dsTcSK and dsTcSH, respectively).
Irrespective of the delivery mechanism a dose-dependent effect was observed for …
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