Coagulopathic complications during extracorporeal life support (ECLS) result from two
parallel processes: 1) foreign surface contact and shear stress during blood circulation and
2) administration of anticoagulant drugs to prevent circuit thrombosis. To address these
problems, biocompatible surfaces are developed to prevent foreign surface-induced
coagulopathy, reducing or eliminating the need for anticoagulants. Tethered liquid
perfluorocarbon (TLP) is a nonadhesive coating that prevents adsorption of plasma proteins …