The role of the liver in autism spectrum disorders (ASD), developmental disabilities
characterized by impairments in social interactions and repetitive behavioral patterns, has
been poorly investigated. In ASD, it has been shown a dysregulation of gut–brain crosstalk,
a communication system able to influence metabolic homeostasis, as well as brain
development, mood and cognitive functions. The liver, with its key role in inflammatory and
metabolic states, represents the crucial metabolic organ in this crosstalk. Indeed, through the …