The aim was to determine the prevalence of infraorbital ethmoid (Haller’s) cells on panoramic radiograph in a group of Thai patients. This study was performed on 500 digital panoramic radiographs from the patients who were referred to radiographic examination for various reasons between January 2018 and February 2020. All radiographs were observed by an oral radiologist for the presence of Haller’s cells. The collected data were analyzed statistically; frequencies/percentages, descriptive statistics, and Chi-square test to obtain the results. From 500 patients, 362 (72.4%) had Haller’s cells. The maximum number of the sample with Haller’s cells were found in the age group of 14-23 years. Among 362 cases with Haller’s cells, 26.4%(132) were ovoid shape. The relationship between pattern of Haller’s cells and side was found to be significant (p= 0.002). In addition, a significant relationship was also observed when the shape and side of the Haller’s cells were correlated, p< 0.001. The results of our study can be used in differential diagnosis of unexplained orofacial pain. The diagnosis of Haller’s cells can provide preoperative information for the surgeon to prevent complications caused by entering these areas. Panoramic radiograph may be an appropriate imaging modality for evaluation of the presence of Haller’s cells.