The core transcriptome of mammalian placentas and the divergence of expression with placental shape
Introduction The placenta is arguably the most anatomically variable organ in mammals
even though its primary function is conserved. Method Using RNA-Seq, we measured the
expression profiles of 55 term placentas of 14 species of mammals representing all major
eutherian superordinal clades and marsupials, and compared the evolution of expression
across clades. Results We identified a set of 115 core genes which is expressed (FPKM≥
10) in all eutherian placentas, including genes with immune-modulating properties (ANXA2 …
even though its primary function is conserved. Method Using RNA-Seq, we measured the
expression profiles of 55 term placentas of 14 species of mammals representing all major
eutherian superordinal clades and marsupials, and compared the evolution of expression
across clades. Results We identified a set of 115 core genes which is expressed (FPKM≥
10) in all eutherian placentas, including genes with immune-modulating properties (ANXA2 …
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