The current state of therapeutic and T cell-based vaccines against human papillomaviruses

A Yang, E Farmer, J Lin, TC Wu, CF Hung - Virus research, 2017 - Elsevier
Human papillomavirus (HPV) is known to be a necessary factor for many gynecologic
malignancies and is also associated with a subset of head and neck malignancies. This
knowledge has created the opportunity to control these HPV-associated cancers through
vaccination. However, despite the availability of prophylactic HPV vaccines, HPV infections
remain extremely common worldwide. In addition, while prophylactic HPV vaccines have
been effective in preventing infection, they are ineffective at clearing pre-existing HPV …
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