… unbudded G 2 arrest and subsequent polyploid titan cell formation is also regulated by the
cell cycle. … Our results show that titan cell formation is cell cycle regulated, and the cyclin Cln1 …

… Titan cells are large, polyploid, display alterations in cell wall … mechanisms that control
titan cell production remains … 4 C after 3 days of incubation in titan cell inducing conditions…

… R265 titan cells produce daughter cells with a polyploid DNA … 7 day old titan and YPD overnight
(control) cells cultures were … following a Stress-Induced G2 Arrest in Cryptococcus. mBio. …

… fascinating switches in cell cycle control and ploidy when it … Polyploidisation takes place
after a G2 arrest and involves … kinetochore attachments in polyploid titan cells are a cause of …

… and can undergo rapid stress-induced karyotypic changes [21]. … after spores are inhaled and
approximately 20% of cells … can enable re-replication of DNA producing polyploid titan cells …

… that cell cycle-regulating genes act in concert to control … to form polyploid titan cells [36]
These distinct cyclin expression … was fixed after cell cycle release from G1/S arrest by growing in …

… is critical for Titan cell formation, and … following cell cycle arrest at G2, which can be induced
by high temperature [75]. It is clear from these examples that a tight control over the cell cycle …

… after the release of the elutriated cells, peaking 45 min after … albicans cell cycle control, we
produced N-terminal … between the G1 cyclins (prolonged accumulation of Cln1, presence of …

… cells endoreduplicate to form uninucleate polyploid titan cells, … follows that the formation of
titan cells is inextricably linked to … cyclin Cln1, required for exit from G2, results in elevated titan …

… titan cells are polyploid and have an increased chitin content. Therefore, we used flow cytometry
to examine the DNA and cell-wall chitin content after … rich YPD (control). Typical 5–7 μm …