… Ectopic Cushing’s syndrome usually relates to the ectopic ACTH syndrome (EAS) and represents
∼20% of ACTH-… The rapidity of onset and the severity of the syndrome have been both …

… Chance or referral bias is also the probable cause of the … of the various neoplastic sources
of ectopic ACTH in the … from the largest published series of ectopic Cushing's syndrome is …

… The probable explanation for the above differences can be found in the facts that the patients
with the ectopic ACTH syndrome tend to have higher levels of plasma ACTH, poorer food …

… The source of ectopic ACTH was not detected in 12% of the "occult" tumors. Once the diagnosis
of the ectopic ACTH syndrome … possible sources of ectopic ACTH should be performed. …

… , proopiomelanocortin and pro-ACTH. Ectopic ACTH syndrome refers to the secretion of
ACTH by non-pituitary tumours, but the predominant circulating form of proopiomelanocortin-…

… We will consider the ectopic ACTH syndrome as a manifestation of the "APUD" concept… the
ectopic ACTH syndrome, namely ectopic production of CRH, as well as CRH along with ACTH…

… [3] have suggested that the term ectopic ACTH syndrome is a misnomer since ACTH, or
Proopiomelanocortin (POMC) immunoreactivity and POMC mRNA have been found in virtually …

… NIH series, which actually included very few patients with SCLC [7], the lung was still the
major source of ectopic ACTH hypersecretion in nearly 50% of tumours localized. Most …

… The ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) was first described in 1928
by Brown as a ‘pluriglandular syndrome of the … cancer and ectopic ACTH secretion (1, 2). …

… come only from understanding the biology of these tumours. In this review we aim to … the
ectopic ACTH syndrome in terms of the possible changes at the level of the POMC gene and the …