The effect of ischemic preconditioning of the pancreas on severity of ischemia/reperfusion-induced pancreatitis after a long period of ischemia in the rat
S Nikeghbalian, P Mardani, MR Mansoorian… - Transplantation …, 2009 - Elsevier
BACKGROUND: The role of ischemia/reperfusion injury in the pathogenesis of acute
pancreatitis is still ill-defined. It is accepted, however, that ischemia/reperfusion induces the
development of postimplantation pancreatitis that is responsible for considerable morbidity.
Preconditioning by brief exposure to ischemia protects the organ against damage evoked by
subsequent severe ischemia. This study was undertaken to examine whether two brief
ischemic periods protect the pancreas against severe ischemia/reperfusion-induced …
pancreatitis is still ill-defined. It is accepted, however, that ischemia/reperfusion induces the
development of postimplantation pancreatitis that is responsible for considerable morbidity.
Preconditioning by brief exposure to ischemia protects the organ against damage evoked by
subsequent severe ischemia. This study was undertaken to examine whether two brief
ischemic periods protect the pancreas against severe ischemia/reperfusion-induced …