[HTML][HTML] The effect of preincisional periportal infiltration with ropivacaine in pain relief after laparoscopic procedures: a prospective, randomized controlled trial

TE Pavlidis, KS Atmatzidis, BT Papaziogas… - JSLS: Journal of the …, 2003 - ncbi.nlm.nih.gov
TE Pavlidis, KS Atmatzidis, BT Papaziogas, JG Makris, CN Lazaridis, TB Papaziogas
JSLS: Journal of the Society of Laparoendoscopic Surgeons, 2003ncbi.nlm.nih.gov
Methods: This prospective, randomized study includes 190 laparoscopic procedures carried
out by the same surgeon. The patients were randomly allocated into 2 groups. The control
group comprised 75 cases of laparoscopic cholecystectomy (LC) and 20 cases of
laparoscopic inguinal hernia repair (LIHR) without the use of a local anesthetic; only saline
was used. The study group comprised 75 cases of LC and 20 cases of LIHR with
preincisional periportal infiltration with 20 mL of ropivacaine (10 mg/mL). The postoperative …
Methods:
This prospective, randomized study includes 190 laparoscopic procedures carried out by the same surgeon. The patients were randomly allocated into 2 groups. The control group comprised 75 cases of laparoscopic cholecystectomy (LC) and 20 cases of laparoscopic inguinal hernia repair (LIHR) without the use of a local anesthetic; only saline was used. The study group comprised 75 cases of LC and 20 cases of LIHR with preincisional periportal infiltration with 20 mL of ropivacaine (10 mg/mL). The postoperative pain scores at 3, 6, 12, and 24 hours determined with a visual analogue scale (VAS), nausea, and the kind and amount of analgesic drugs were assessed.
Results:
In the study group in 41% of LC cases and 85% of LIHR cases, no analgesia was required at all; likewise, in the control group in 20% of LC cases and 44% of LIHR cases, no analgesia was required. The difference was statistically significant (P< 0.05). In the remainder, pain at 3 and 6 hours and total analgesic requirements in the study group were less than that in the control group (P< 0.05). The postoperative nausea and shoulder pain remained statistically unchanged (P> 0.05).
Conclusions:
It seems that wound infiltration with ropivacaine in laparoscopy provides satisfactory postoperative analgesia, diminishing or reducing the need for opioids.
ncbi.nlm.nih.gov
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