This study aims to analyze how science process skills use scientific inquiry, to analyze how science process skills with high scientific attitude and low scientific attitude, to analyze the interaction between scientific inquiry and scientific attitude. This type of research is a quasi experiment with a pretest-posttest control group design. Data analysis was performed using descriptive analysis which aims to be able to explain and predict the symptoms that apply on the basis of data obtained in the field. Based on the results of the study it was found that the science process skills using scientific inquiry on the temperature and heat material experienced a significant increase, the skills that had a high scientific attitude were better than the science process skills which had a low scientific attitude, and there was an interaction between scientific inquiry and scientific attitude.