The emergence of flow cytometry for sensitive, real-time measurements of molecular interactions
JP Nolan, LA Sklar - Nature biotechnology, 1998 - nature.com
JP Nolan, LA Sklar
Nature biotechnology, 1998•nature.comThe analysis of macromolecular interactions is an essential element of biomedical research.
Flow cytometry is uniquely capable of making sensitive and quantitative measurements of
molecular interactions. These measurements can be made in real time with subsecond
kinetic resolution using purified biomolecules or living cells. Combined with automated
sample handling, these features make flow cytometry a versatile and robust technology for
the analysis of molecular interactions.
Flow cytometry is uniquely capable of making sensitive and quantitative measurements of
molecular interactions. These measurements can be made in real time with subsecond
kinetic resolution using purified biomolecules or living cells. Combined with automated
sample handling, these features make flow cytometry a versatile and robust technology for
the analysis of molecular interactions.
Abstract
The analysis of macromolecular interactions is an essential element of biomedical research. Flow cytometry is uniquely capable of making sensitive and quantitative measurements of molecular interactions. These measurements can be made in real time with subsecond kinetic resolution using purified biomolecules or living cells. Combined with automated sample handling, these features make flow cytometry a versatile and robust technology for the analysis of molecular interactions.
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