… liver pre-metastatic niche (PMN) remain incompletely understood. To investigate the role of
CRC-derived EVs in the remodeling of the liver … that tumor cells evaded the immune system’s …

… play a central role in inducing immune tolerance to innocuous antigens that reached the …
number of niches. However, during liver development, the majority of liver niches are taken by …

… Although once considered to consist solely of a single population of resident Kupffer cells
(KCs), we now know that both the murine and human liver harbor multiple populations of …

… number of cases of advanced liver disease and in liver-related mortality in the coming years…
of cellular debris, iron homeostasis and in the modulation of immune response [176]; indeed, …

… , the space of Disse is a stellate cell niche within rat liver, a novel function of this unique organ
structure. This niche … to maintain the characteristics of HSCs and to retain them within the …

… Although compelling evidence exists that the immune response to primary colorectal cancer
… evidence to suggest that the immune cell infiltrate within the metastatic niche was of similar …

… The liver is the largest solid organ in our body receiving every day more than 2,000 liters of
… anatomical identities that reflect the impact of this peculiar tissue-niche in generating either …

… To unravel the divergent role of LSECs in modulating liver repair, we used a single injection
… To elucidate the mechanism underlying the pro-fibrotic drift of LSEC niche, we conditionally …

… can interact with HPCs including cholangiocytes, hepatocytes, stellate cells, myofibroblasts,
Kupffer cells, LSECs and cells from the immune system such as macrophages and …

… Hepatocyte transplantation into the native liver has been proposed as an alternative to liver
… Involvement of the innate immune system in liver regeneration and injury. J Hepatol. 2006;…