The impact of treatment time and smoking on local control and complications in T1 glottic cancer

JCM van der Voet, RB Keus, AAM Hart… - International Journal of …, 1998 - Elsevier
Purpose: To define the optimal treatment regimen, patients with T1N0M0 glottic larynx
carcinoma were treated with six different radiotherapy (RT) schedules. To assess the
influence of patient characteristics, complication rates, and to evaluate the overall larynx
preservation. Methods and Materials: Out of a consecutive series of 383 patients treated for
T1N0M0 glottic larynx carcinoma between 1965 and 1992, 352 evaluable patients were
treated with six different “standard” fractionation schedules: 65 Gy (20× 3.25 Gy), 62 Gy (20× …
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