As an interface with the environment, the skin is a complex ecosystem colonized by many
microorganisms that coexist in an established balance. The cutaneous microbiome inhibits
colonization with pathogens, such as Staphylococcus aureus, and is a crucial component for
function of the epidermal barrier. Moreover, crosstalk between commensals and the immune
system is now recognized because microorganisms can modulate both innate and adaptive
immune responses. Host-commensal interactions also have an effect on the developing …