Amelogenins, major components of developing enamel, are predominantly involved in the
formation of tooth enamel. Although amelogenins are also implicated in cementogenesis,
their precise spatial expression pattern and molecular role are not clearly understood. Here,
we report for the first time the expression of two alternate splice forms of amelogenins, M180
and the leucine-rich amelogenin peptide (LRAP), in the periodontal region of mouse tooth
roots. Lack of M180 and LRAP mRNA expression correlated with cementum defects …