The role of photochemical treatment with amotosalen and UV-A light in the prevention of transfusion-transmitted cytomegalovirus infections
JD Roback, M Conlan, WL Drew, P Ljungman… - Transfusion Medicine …, 2006 - Elsevier
Primary cytomegalovirus (CMV) infection is usually asymptomatic in immunocompetent
patients but can cause serious life-threatening complications in immunocompromised CMV-
seronegative patients, including patients receiving a bone marrow or peripheral blood stem
cell transplant, recipients of some solid-organ transplants, and low-birth-weight neonates.
Current recommendations for preventing transfusion-transmitted CMV (TT-CMV) infection in
these patients include exclusive use of CMV-seronegative and/or leukoreduced cellular …
patients but can cause serious life-threatening complications in immunocompromised CMV-
seronegative patients, including patients receiving a bone marrow or peripheral blood stem
cell transplant, recipients of some solid-organ transplants, and low-birth-weight neonates.
Current recommendations for preventing transfusion-transmitted CMV (TT-CMV) infection in
these patients include exclusive use of CMV-seronegative and/or leukoreduced cellular …
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