The role of steroids and their effects on phospholipase A2: An animal model of radiculopathy

HM Lee, JN Weinstein, ST Meller, N Hayashi, KF Spratt… - Spine, 1998 - journals.lww.com
… in a reliable animal model for lumbar radiculopathy, and the … in the irritated nerve root model
were caused in part by a high … there are some adverse effects caused by epidural steroid

The Role of Steroids and Their Effects on Phospholipase A2

HM Lee - Spine, 2000 - journals.lww.com
… Several papers have been recently published regarding the role of local acting
inflammatory agents to the spinal roots and the role of antiinflammatory agents or/and …

The role of steroids and their effects on phospholipase A2

PG Korovessis - Spine, 2000 - journals.lww.com
… Several papers have been recently published regarding the role of local acting
inflammatory agents to the spinal roots and the role of antiinflammatory agents or/and …

… -induced reduction of proinflammatory phospholipase A2 activity and amelioration of neuropathic behavioral changes in an in vivo model of acute sciatica

PD Sawin, VC Traynelis, G Rich, BA Smith… - Journal of …, 1997 - thejns.org
… However, the success of therapeutic modalities (such as epidural corticosteroid injection) …
for inflammation in several human and animal models.Phospholipase A2 belongs to a class of …

Pathophysiology of lumbar radiculopathies and the pharmacology of epidural corticosteroids and local anesthetics

JP Robinson, PB Brown, JD Fisk - Physical Medicine and Rehabilitation …, 1995 - Elsevier
… be secondary to chemical rather than mechanical effects of the ligatures.3s, 36 Third, very
high levels of the known inflammatory mediator phospholipase A2 have been found in human …

Therapeutic spinal corticosteroid injections for the management of radiculopathies

CW Slipman, DW Chow - Physical Medicine and Rehabilitation …, 2002 - pmr.theclinics.com
… High levels of inflammatory phospholipase A2 activity in lumbar disc herniations. … ], using
an animal model, demonstrated that anesthetic agents impeded normal radicular blood flow …

Biochemistry of Epidural Steroid Injections

POFRS PAIN - Basic Science of Spinal Diseases, 2013 - books.google.com
… for patients with lumbar radiculopathy associated with herniated nucleus … Phospholipase A2
releases arachidonic acid from … 50 Another animal model suggested that glucocorticoids can …

Roles of thromboxane A2 and leukotriene B4 in radicular pain induced by herniated nucleus pulposus

M Kawakami, T Matsumoto… - Journal of Orthopaedic …, 2001 - Wiley Online Library
… The role of steroids and their effects on phospholipase A2 an animal model of radiculopathy
Human group 11 phospholipase A2 in normal and diseased intervertebral discs. Biochem …

[PDF][PDF] Epidural steroids in the management of chronic spinal pain and radiculopathy

MV Boswell, HC Hansen, AM Trescot, JA Hirsch - Pain Physician, 2003 - researchgate.net
… injections in managing lumbar radiculopathy was moderate, while there was limited or in…
The role of steroids and their effects on phospholipase A2. An animal model of radiculopathy

Do corticosteroids produce additional benefit in nerve root infiltration for lumbar disc herniation?

H Tachihara, M Sekiguchi, S Kikuchi, S Konno - Spine, 2008 - journals.lww.com
… -1, TNF and phospholipase A2. In patients with LDH, elevated levels of phospholipase A2, …
reactions may play an important pathogenic role in causing sciatica after disc herniation. As …