Prolonged periods of demanding cognitive tasks lead to an exhausted feeling known as
mental fatigue. The neural underpinnings of mental fatigue are still under exploration. In the
present study, we aimed to identify neurophysiological indicators of mental fatigue by
studying the time–frequency distribution of the event-related potentials (ERPs) measured in
N= 26 adults in nonfatigued versus fatigued states. We were interested in the frontal theta
and occipital alpha variations, which have shown consistent relationships with mental …