The O2: N2 ratio induce different morphology of the depositions, especially grain size and protein adhesion from albumin supplemented SBF. Once with the increasing of the nitrogen content, the adsorption of albumin decreases significantly. The best results are obtained for the samples TiOxNy having a O2: N2 ratio of 1: 1 where, practically, no protein or salts deposition occurs after 8 or only limited depositions at the wrists are where some detaching appear. These data open new perspectives in using these titanium oxynitrides as coating materials for stents and other metallic implants where limited/selective adsorption are needed to avoid the failure of the implants.