Current influenza virus vaccines are annually reformulated to elicit protection by generating
an immune response toward the virus strains that are predicted to circulate in the upcoming
influenza season. These vaccines provide limited protection in cases of antigenic mismatch,
when the vaccine and the circulating viral strains differ. The emergence of unexpected
pandemic viruses presents an additional challenge to vaccine production. To increase
influenza virus preparedness, much work has been dedicated to the development of a …