Background Few studies have yielded information on comparative effectiveness of
transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement
(SAVR) procedures in a real-world setting. The aim of this analysis is to describe procedural
and post-procedural outcomes in a TAVI/SAVR intermediate risk propensity-matched
population. Methods OBSERVANT is an observational prospective multicenter cohort study,
enrolling AS patients undergoing SAVR or TAVI. Propensity score method was applied to …

Background Severe aortic valve stenosis (AS) is a major cause of morbidity and mortality
worldwide. The definitive management for severe AS is aortic valve replacement (AVR). The
choice of transcatheter approach versus open‐heart surgery for AVR in people with severe
AS and low surgical risk remains a matter of debate. Objectives To assess the benefits and
harms of transcatheter aortic valve implantation (TAVI) compared to surgical aortic valve
replacement (SAVR) in people with severe AS and low surgical risk.