Transcriptomic profiling identifies host-derived biomarker panels for assessing cerebral malaria

E Asiedu, A Larbi, E Adankwah, JK Yambah, SA Sakyi… - Gene Reports, 2022 - Elsevier
Cerebral malaria (CM) is a rare but fatal form of severe malaria sequelae. Host-derived
biomarkers have the potential to assist in the early assessment, diagnosis, and prognosis of
CM. However, previously reported host-derived CM biomarkers have limited clinical utility
despite their ability to discriminate between CM and non-CM conditions, either due to their
specificity to other non-malaria conditions or consist of many biomarkers for test
implementation. Here, we describe the identification of host-derived transcriptomic …
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