Transient osteoporosis: clinical spectrum in adults and associated risk factors
Objective: We aimed to describe the natural history of the rare clinical syndrome of transient
osteoporosis (TO) and ascertain potential risk factors. Methods: Retrospective cohort study
of adults with TO at Mayo Clinic, Rochester, Minnesota, over 15 years. Adults with acute-
onset joint pain worsened by weight bearing and bone marrow edema on magnetic
resonance imaging were included; exclusion criteria were trauma, tumors, rheumatic
diseases, avascular necrosis, infection, and hyperesthesia. Results: Thirty-three patients …
osteoporosis (TO) and ascertain potential risk factors. Methods: Retrospective cohort study
of adults with TO at Mayo Clinic, Rochester, Minnesota, over 15 years. Adults with acute-
onset joint pain worsened by weight bearing and bone marrow edema on magnetic
resonance imaging were included; exclusion criteria were trauma, tumors, rheumatic
diseases, avascular necrosis, infection, and hyperesthesia. Results: Thirty-three patients …
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