… inflammation at the cellular, small animal, large animal, and human levels. As such, Translational
Systems Biology … current state of Translational Systems Biology, including overviews of …

… provided a detailed view of signaling under inflamed and uninflamed conditions (10, 11), …
translational systems biology uses computational systems models to better translate biological …

OBJECTIVE Type 2 diabetes and obesity are increasingly affecting human populations
around the world. Our goal was to identify early molecular signatures predicting genetic risk to …

… studies to elucidate the effects of targeted interventions in inflammatory … as an inflammatory
disease, demonstrated multi-system effects of chronic inflammation and refined translational …

… of the inflammatory response share much of their cell biology … Given that too little or too
much inflammation can be the root … those cell biology aspects of the inflammatory response that …

… make acute inflammation and critical illness a complex system are a … the use of systems and
computational biology approaches in order to … Translational systems biology of inflammation …

… important from a translational perspective. Systems biology represents an especially
challenging field in terms of data availability. In general, complex systems biology models (…

… Chronic inflammatory pulmonary diseases such as COPD … through an integrative systems
biology research strategy … processing or reversible post-translational modifications such as …

… Recognizing remaining challenges in the field, we provide an outlook regarding the
translational potential of the systems biology approach to inflammatory signaling in the clinical …

… The hope of the rapid translation of 'genes to drugs' has foundered on the reality that …
inflammatory cytokines 32 . Clustering of drug-induced profiles from inflammatory model systems (…