Decoding Systems Biology of Inflammation Signatures in Cancer Pathogenesis: Pan-Cancer Insights from 12 Common Cancers
B Turanli - OMICS: A Journal of Integrative Biology, 2023 - liebertpub.com
… However, the underlying mechanisms of inflammatory signaling in the … of inflammation-associated
proteins that lead to tumorigenesis, and with an eye to discovery of potential system …
proteins that lead to tumorigenesis, and with an eye to discovery of potential system …
Connecting aging biology and inflammation in the omics era
KA Walker, N Basisty, DM Wilson… - The Journal of Clinical …, 2022 - Am Soc Clin Investig
… and one with powerful potential for translation. Work on biomarkers searching for signatures
that discriminate between different aspects and triggers of inflammation is currently ongoing. …
that discriminate between different aspects and triggers of inflammation is currently ongoing. …
The translational revolution and use of biologics in patients with inflammatory skin diseases
… to suppression of immune responses and reversal of pathologic epidermal responses,
suggesting a primary immune model.3, 10, 11, 12 These opened the door for the translational …
suggesting a primary immune model.3, 10, 11, 12 These opened the door for the translational …
The GAIT system: a gatekeeper of inflammatory gene expression
… of inflammatory mRNAs and suppresses their translation. … translation initiation by binding
eukaryotic initiation factor 4G. Repression of a post-transcriptional regulon by the GAIT system …
eukaryotic initiation factor 4G. Repression of a post-transcriptional regulon by the GAIT system …
Approaches to evaluate lung inflammation in translational research
… Stratification of approaches to assess lung inflammation can … Each technique to evaluate
lung inflammation has advantages … to increase the rigor and translational significance of data. …
lung inflammation has advantages … to increase the rigor and translational significance of data. …
Heterogeneity in mechanisms influencing glucocorticoid sensitivity: the need for a systems biology approach to treatment of glucocorticoid-resistant inflammation
CR Keenan, D Radojicic, M Li, A Radwan… - Pharmacology & …, 2015 - Elsevier
… also produce secondary post-transcriptional and translational effects. GR transactivation can
… GR transcriptional activity can also modulate the expression level of translational initiation …
… GR transcriptional activity can also modulate the expression level of translational initiation …
Addressing the translational dilemma: dynamic knowledge representation of inflammation using agent-based modeling
G An, S Christley - Critical Reviews™ in Biomedical …, 2012 - dl.begellhouse.com
… Translational systems biology using an agentbased approach for dynamic knowledge
representation: an evolutionary paradigm for biomedical research. Wound Repair Regen. 2010 …
representation: an evolutionary paradigm for biomedical research. Wound Repair Regen. 2010 …
Role of neutrophils in innate immunity: a systems biology‐level approach
SD Kobayashi, FR DeLeo - … Reviews: Systems Biology and …, 2009 - Wiley Online Library
… transcriptional/translational systems serve … systems biology-level approaches have been
instrumental in reshaping our view of the role of neutrophils in the resolution of the inflammatory …
instrumental in reshaping our view of the role of neutrophils in the resolution of the inflammatory …
Systems biology and the future of medicine
J Loscalzo, AL Barabasi - … Reviews: Systems Biology and …, 2011 - Wiley Online Library
… The translation of new knowledge about mechanisms that … A major contributor to this
translational delay is the use of the … (eg, anti-inflammatory or antithrombotic therapies for acute …
translational delay is the use of the … (eg, anti-inflammatory or antithrombotic therapies for acute …
Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli
D Hodgson, AD Rowan, F Falciani… - … computational biology, 2019 - journals.plos.org
… However, the mechanism by which TGFβ protects against pro-inflammatory responses …
systems biology to combine experimental and computational outputs to examine how the system …
systems biology to combine experimental and computational outputs to examine how the system …