Transoral robotic surgery for recurrent cancers of the upper aerodigestive tract—systematic review and meta‐analysis

J Hardman, ZW Liu, G Brady, J Roe, C Kerawala… - Head & …, 2020 - Wiley Online Library
J Hardman, ZW Liu, G Brady, J Roe, C Kerawala, F Riva, P Clarke, D Kim, S Bhide…
Head & Neck, 2020Wiley Online Library
Background Transoral robotic surgery (TORS) for recurrent head and neck (H&N) cancer is
an emerging but relatively infrequent procedure. Methods Systematic review and meta‐
analysis of studies reporting survival data and functional outcomes for patients undergoing
TORS for previously treated H&N cancers. Results Eight hundred seventy‐eight records
were identified, of which eight were eligible for inclusion, covering 161 cases (range 1‐64).
The pooled rates were as follows: 2‐year overall survival 73.8%(4 studies, range 70.6‐75.0 …
Background
Transoral robotic surgery (TORS) for recurrent head and neck (H&N) cancer is an emerging but relatively infrequent procedure.
Methods
Systematic review and meta‐analysis of studies reporting survival data and functional outcomes for patients undergoing TORS for previously treated H&N cancers.
Results
Eight hundred seventy‐eight records were identified, of which eight were eligible for inclusion, covering 161 cases (range 1‐64). The pooled rates were as follows: 2‐year overall survival 73.8% (4 studies, range 70.6‐75.0, 95% confidence intervals (CI) 65.4 to 81.5, [I2 0.0%, P = 1.0]); 2‐year disease‐free survival 74.8% (4 studies, range 56.2‐92.0, 95% CI 63.3 to 84.8, [I2 36.9%, P = .2]); postoperative hemorrhage 9.3% (4 studies, range 3.3‐13.3, 95% CI 4.7 to 15.1, [I2 0.0%, P = .5]).
Conclusions
Functional and oncological outcomes are favorable, although the follow‐up is limited in the literature. Larger cohorts with longer follow‐up are needed for definitive conclusions to be drawn.
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