… about the best approach to treat this serious disorder. Here, we discuss the treatment options
for depression in children and adolescents. Major depressive disorder is common during …

… ’s effectiveness in treating depression in youth is not robust. Pooled data from two studies
comparing sertraline 50–200 mg daily for 10 weeks versus placebo in depressed children and …

… , depressive disorders are frequently chronic, with almost three-fourths of depressed children
having subsequent depressive … patients will need chronic treatment rather than intervention …

… and pharmacological treatments for children and adolescents with a confirmed diagnosis
of a depressive disorder (DD)—major depressive disorder (MDD), persistent …

… We focus on unipolar depression because the majority of … unipolar depression or on
depressed children and adolescents. … of depressive disorders in childhood and adolescence. We …

… including children and adolescents with major depressive … be effective in treating depression
in children and adolescents. If … referral to a child or adolescent psychiatrist is recommended. …

… , and treatment noncompliance. Selective serotonin reuptake inhibitors (SSRIs) are the
first-line treatment for depression in children and adolescents. For treatment-resistant depression, …

… of depressive phenomena in childhood and adolescence and the impact of early depressive
experiences on later functioning have increased, the need for effective treatments has …

… depressed children and adolescents are effective. New directions in research on the nature
of depression in children and adolescents … existing in depressed children and adolescents. …

… of depression are persistent in the depressed child in spite of preliminary psychosocial
interventions, then the initial decision is which medication to use as the first line of treatment. …