Triptorelin-functionalized PEG-coated biosynthesized gold nanoparticles: Effects of receptor-ligand interactions on adhesion to triple negative breast cancer cells
This paper presents the results of an experimental and computational study of the adhesion
of triptorelin-conjugated PEG-coated biosynthesized gold nanoparticles (GNP-PEG-TRP) to
triple-negative breast cancer (TNBC) cells. The adhesion is studied at the nanoscale using a
combination of atomic force microscopy (AFM) experiments and molecular dynamics (MD)
simulations. The AFM measurements showed that the triptorelin-functionalized gold
nanoparticles (GNP-TRP and GNP-PEG-TRP) have higher adhesion to triple-negative …
of triptorelin-conjugated PEG-coated biosynthesized gold nanoparticles (GNP-PEG-TRP) to
triple-negative breast cancer (TNBC) cells. The adhesion is studied at the nanoscale using a
combination of atomic force microscopy (AFM) experiments and molecular dynamics (MD)
simulations. The AFM measurements showed that the triptorelin-functionalized gold
nanoparticles (GNP-TRP and GNP-PEG-TRP) have higher adhesion to triple-negative …